პანელი მოიცავს 500-ზე მეტი გენის შესწავლსა, MSI, TMB-ისა და HRD-ის შეფასებას:

A

A1CF, ABCB1, ABL1, ABL2, ABRAXAS1, ACSM2B, ACVR1, ACVR1B, ACVR2A, ADAM18, ADAMTS12, ADAMTS2, AKT1, AKT2, AKT3, ALK, AMER1, ANO4, APC, AR, ARAF, ARHGAP35, ARID1A, ARID1B, ARID2, ARID5B, ARMC4, ASXL1, ASXL2, ATM, ATP1A1, ATR, ATRX, AURKA, AURKB, AURKC, AXIN1, AXIN2, AXL

B

B2M, BAP1, BARD1, BCL2, BCL2L12, BCL6, BCOR, BCR, BLM, BMP5, BMPR2, BRAF, BRCA1, BRCA2, BRINP3, BRIP1, BTK

C

C6, C8A, C8B, CACNA1D, CALR, CANX, CARD11, CASP8, CASR, CBFB, CBL, CCND1, CCND2, CCND3, CCNE1, CD163, CD274, CD276, CD79B, CDC73, CDH1, CDH10, CDK12, CDK4, CDK6, CDKN1A, CDKN1B, CDKN2A, CDKN2B, CDKN2C, CHD4, CHEK1, CHEK2, CIC, CIITA, CNTN6, CNTNAP4, CNTNAP5, COL11A1, CREBBP, CSF1R, CSMD3, CTCF, CTLA4, CTNNB1, CTNND2, CUL1, CUL3, CUL4A, CUL4B, CYLD, CYP2C9, CYP2D6, CYSLTR2

D

DAXX, DCAF4L2, DCDC1, DDR1, DDR2, DDX3X, DGCR8, DICER1, DNMT3A, DOCK3, DPYD, DROSHA, DSC1, DSC3

E

E2F1, EGFR, EIF1AX, ELF3, EMSY, ENO1, EP300, EPAS1, EPCAM, EPHA2, ERAP1, ERAP2, ERBB2, ERBB3, ERBB4, ERCC2, ERCC4, ERCC5, ERG, ERRFI1, ESR1, ETV1, ETV4, ETV5, ETV6, EZH2

F

FAM135B, FANCA, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FAS, FAT1, FBXW7, FGF19, FGF23, FGF3, FGF4, FGF7, FGF9, FGFR1, FGFR2, FGFR3, FGFR4, FLT3, FLT4, FOXA1, FOXL2, FOXO1, FUBP1, FYN

G

GALNT17, GATA2, GATA3, GLI1, GLI3, GNA11, GNA13, GNAQ, GNAS, GPR158, GPS2, GRID2

H

H1-4, H2BC5, H3-3A, H3-3B, H3C2, HCN1, HDAC2, HDAC9, HIF1A, HLA-A, HLA-B, HLA-C, HNF1A, HRAS

I

ID3, IDH1, IDH2, IGF1R, IKBKB, IL6ST, IL7R, INPP4B, IRF4, IRS4

J

JAK1, JAK2, JAK3

K

KCND2, KCNH7, KCNJ5, KDM5C, KDM6A, KDR, KEAP1, KEL, KIR3DL1, KIT, KLF4, KLF5, KLHL13, KMT2A, KMT2B, KMT2C, KMT2D, KNSTRN, KRAS, KRTAP21-1, KRTAP6-2

L

LARP4B, LATS1, LATS2, LRRC7

M

MAGOH, MAP2K1, MAP2K2, MAP2K4, MAP2K7, MAP3K1, MAP3K4, MAP3K8, MAPK1, MAPK8, MARCO, MAX, MCL1, MDM2, MDM4, MECOM, MED12, MEF2B, MEN1, MET, MGA, MITF, MLH1, MLH3, MPL, MRE11, MSH2, MSH3, MSH6, MTAP, MTOR, MTUS2, MUTYH, MYB, MYBL1, MYC, MYCL, MYCN, MYD88, MYOD1

N

NBN, NCOR1, NF1, NF2, NFE2L2, NLRC5, NOL4, NOTCH1, NOTCH2, NOTCH3, NOTCH4, NRAS, NRG, NRXN1, NSD2, NT5C2, NTRK1, NTRK2, NTRK3, NUP93, NUTM1, NYAP2

O

OR10G8, OR2G6, OR2L13, OR2L2, OR2L8, OR2M3, OR2T3, OR2T33, OR2T4, OR2W3, OR4A15, OR4C15, OR4C6, OR4M1, OR4M2, OR5D18, OR5F1, OR5L1, OR5L2, OR6F1, OR8H2, OR8I2, OR8U1, ORC4

P

PAK5, PALB2, PARP1, PARP2, PARP3, PARP4, PAX5, PBRM1, PCBP1, PCDH17, PDCD1, PDCD1LG2, PDE1A, PDE1C, PDGFRA, PDGFRB, PDIA3, PGD, PHF6, PIK3C2B, PIK3CA, PIK3CB, PIK3CD, PIK3CG, PIK3R1, PIK3R2, PIM1, PLCG1, PLXDC2, PMS1, PMS2, POLD1, POLE, POM121L12, POT1, PPARG, PPFIA2, PPM1D, PPP2R1A, PPP2R2A, PPP6C, PRDM1, PRDM9, PRKACA, PRKACB, PRKAR1A, PSMB10, PSMB8, PSMB9, PTCH1, PTEN, PTPN11, PTPRD, PTPRT, PXDNL

R

RAC1, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RAD52, RAD54L, RAF1, RARA, RASA1, RASA2, RB1, RBM10, RBP3, RECQL4, REG1A, REG1B, REG3A, REG3G, RELA, RET, RGS7, RHEB, RHOA, RICTOR, RIT1, RNASEH2A, RNASEH2B, RNASEH2C, RNF43, ROS1, RPA1, RPL10, RPL22, RPL5, RPS6KB1, RPTN, RPTOR, RSPO2, RSPO3, RUNDC3B, RUNX1, RUNX1T1

S

SDHA, SDHB, SDHC, SDHD, SETBP1, SETD2, SF3B1, SH3RF2, SIX1, SIX2, SLC15A2, SLC8A1, SLCO1B3, SLX4, SMAD2, SMAD4, SMARCA4, SMARCB1, SMC1A, SMO, SNCAIP, SOCS1, SOS1, SOX2, SOX9, SPEN, SPOP, SRC, SRSF2, STAG2, STAT1, STAT3, STAT5B, STAT6, STK11, SUFU, SYT10, SYT16

T

TAF1, TAP1, TAP2, TAPBP, TBX3, TCF7L2, TERT, TET2, TFE3, TFEB, TGFBR1, TGFBR2, TMEM132D, TNFAIP3, TNFRSF14, TOP1, TOP2A, TP53, TP63, TPMT, TPP2, TPTE, TRHDE, TRIM48, TRIM51, TRRAP, TSC1, TSC2, TSHR

U

U2AF1, UGT1A1, USP8, USP9X

V

VHL

W

WAS, WT1

X

XPO1, XRCC2, XRCC3

Y

YAP1, YES1

Z

ZBTB20, ZFHX3, ZIM3, ZMYM3, ZNF217, ZNF429, ZNF479, ZNF536, ZRSR2